Ovarian cancer: Clinical analysis of 209 cases

ABSTRACT

Two hundred and nine ovarian cancer cases were treated between January 1974 and December 1988. The median age was 45 years. The commonest symptoms were abdominal distension, pain and uterine bleeding. The commonest histology was the common epithelial variety [79%]. Half of the cases were in stage III and IV, and 61% had histopathological grades 3 and 4. Seventy four percent women had postoperative residual tumor more than 2 cm in diameter. Radiotherapy induced total response of 38.6% in 101 cases, and chemotherapy induced total response of 58.3% in 60 cases. The five year actuarial survival was 30%, 39%, 26% for common epithelial, germ cell and sex cord tumors respectively. The most important prognostic factors were the initial stage, size of the residual tumor, and unfavorable histology