ICAM-1 and L-selectins: the cell adhesion molecules among children with nephrotic syndrome
Egyptian Medical Journal of the National Research Center. 2003; 2 (2): 35-53
em Inglês
| IMEMR
| ID: emr-121091
ABSTRACT
In this study, intercellular adhesion molecules [ICAM-1] and L-selectin were described in sera from 36 children suffering from idiopathic nephrotic syndrome by using ELISA. They were classified into three groups Group I, 26 patients with minimal change nephritic syndrome [MCNS]; group II, 10 cases of non-minimal change nephrotic syndrome [MCNS] [6 cases of mesangioproliferative and 4 cases of focal segmental glomerulosclerosis] and group III,15 healthy children were enrolled to serve as controls. Patients within group I were reexamined according to the disease activity and steroid therapy. The study concluded that the elevation in serum ICAM-1 and L-selectin in MCNS and non-MCNS groups compared with the healthy controls could provide the basis for disturbance in T cell function in patients with nephrosis, suggesting that the disease is mediated by immunologic mechanisms disturbing the cellular immunity
Buscar no Google
Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Ensaio de Imunoadsorção Enzimática
/
Moléculas de Adesão Celular
/
Selectina L
/
Imunidade Celular
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Egypt. Med. J. Natl. Res. Cent.
Ano de publicação:
2003
Similares
MEDLINE
...
LILACS
LIS