Serum lipid profile in patients with chronic renal failure before and after renal transplantation

ABSTRACT

Serum lipid profile was investigated in 15 patients with chronic renal failure who were on regular hemodialysis. Serum samples were taken before and 1, 3 and 6 months after renal transplantation to find any changes in the lipid profile which may occur in these patients. The results of the study showed significant progressive elevation in serum triglycerides, cholesterol, LDL, and apo-B lipoprotein giving their highest level at the 6th month after renal transplantation. On the other hand, HDL and apo-A lipoprotein serum levels were significantly increased giving their highest level one month after transplantation. These findings point to the important role of lipid abnormalities in the pathogenesis of post transplantation atherosclerosis which may allow to identify patients at risk earlier