LMJ-Lebanese Medical Journal. 2002; 50 (1-2): 32-8
em Inglês
| IMEMR
| ID: emr-122243
ABSTRACT
Angiogenesis, the formation of new blood vessels from pre-existing ones, is a very well controlled multistep process under physiologic conditions. It involves a balance between several positive and negative regulators. Pathologic angiogenesis, both-excessive and insufficient, plays a role in the pathophysiology of many diseases including cancer. It has been proven that tumor growth and metastasis are angiogenesis-dependent. Endothelial cells and tumor cells also provide a mutual support to each other via the secretion of several substances. Targeting tumor blood vessels is a new approach to the treatment of cancer. Clinical trials are currently underway and the results appear to be very promising
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Neovascularização Fisiológica
/
Inibidores da Angiogênese
/
Neoplasias
Idioma:
Inglês
Revista:
Lebanese Med. J.
Ano de publicação:
2002
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