Antimicrobial agent- resistance in Escherichia coli, isolated from patients with diarrhea in Aden

ABSTRACT

The potency of five types of antimicrobial agents, tested against four Escherichia coli isolates and causing diarrhea in patients, in Aden were evaluated. The production of the beta-lactamase was also evaluated by using direct capillary tubes method. Ofloxacin was the most antimicrobial agent with the highest susceptibility rate and the most active compound among the E. coli isolates [100% susceptible], followed by tetracycline [75% susceptible] and ampicillin [50% susceptible]. The resistance rates to cefpodoxime [100% resistance] and amoxi-clavu. [75% resistance] were high among the isolates in this study. The studied E. coli isolates demonstrated high resistance rates to beta-lactam drugs, including amoxicillin- beta-lactamase inhibitor combination [amoxi-clavu.]. The production of beta-lactamase among the studied E.coli isolates [25%] and, therefore, did not contribute significantly to the resistance of these isolates. The results presented in this study confirm that bacterial resistance continues to be a great problem in Aden