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Clinicopathologic characteristics and therapeutic outcomes of primary gastrointestinal non-Hodgkin's lymphomas: 10 years of experience from a single center in Eastern Anatolia
Medical Principles and Practice. 2009; 18 (5): 399-406
em Inglês | IMEMR | ID: emr-123153
ABSTRACT
The objective of this retrospective study was to report the clinicopathological data and the treatment outcomes in patients with primary gastrointestinal non-Hodgkin's lymphoma. We carried out a retrospective analysis of 41 patients [22 females, 18 males, median age 58 and range 18-90 years] who presented to our department with histopathological diagnosis of primary gastrointestinal non-Hodgkin's lymphoma between 1995 and 2004. The stomach was the most common extranodal site and was seen in 25 of 41 [61%] patients. At presentation 28 [68.3%] patients had gastrointestinal symptoms while 27 [65.9%] had B symptoms. The range of follow-up was 2-84 months with a median of 9 months. The overall survival rate was 3 years for 25 [61.21%] patients. The 3-year overall survival rate was better in patients with early-stage disease [stages I and II[1]] who were treated with surgery plus chemotherapy and/or radiation therapy than in those treated with chemotherapy alone [91.6 vs. 50%, p<0.05]. The disease had a significant impact on both the progression-free survival and overall survival rates. Our data showed that surgical resection prior to postoperative chemotherapy was a better option for patients with early-stage disease with better patient survival
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Análise de Sobrevida / Resultado do Tratamento / Intervalo Livre de Doença / Neoplasias Gastrointestinais Limite: Feminino / Humanos / Masculino Idioma: Inglês Revista: Med. Princ. Pract. Ano de publicação: 2009

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Análise de Sobrevida / Resultado do Tratamento / Intervalo Livre de Doença / Neoplasias Gastrointestinais Limite: Feminino / Humanos / Masculino Idioma: Inglês Revista: Med. Princ. Pract. Ano de publicação: 2009