Effect of diclofenac sodium on increased menstrual blood loss associated with intrauterine contraception

ABSTRACT

The menstrual blood loss [MBL] was quantitatively estimated prior to IUD insertion in 50 females attending the family planning clinic. After insertion, the MBL was re-estimated monthly for 6 months and then after the 11th and 12th month post-insertion. Diclofenac sodium oral tablets [50 mg] were given at the onset of menses and for 5 consecutive days at the 2nd, 4th, 6th, and 12th month after IUD insertion. The MBL increased significantly after the unmedicated post-insertion cycles. With the medicated cycles, the MBL decreased significantly when compared to the preceding unmedicated ones. A beneficial effect on IUD-induced pain observed, no effect was found on the intermenstrual spotting. Side effects of medication were mild and did not necessitate withdrawal from the study