Evaluation of inter-pandemic influenza vaccine effectiveness during eight consecutive winter seasons in England and Wales in patients with cardiovascular risk factors
Journal of Infection and Public Health. 2010; 3 (4): 159-165
em Inglês
| IMEMR
| ID: emr-125903
ABSTRACT
We evaluated the effectiveness of inactivated influenza vaccine in persons aged >/= 45 years with co-morbidities [including essential hypertension] likely to have prompted consideration of prophylactic statin therapy. Using case-control analyses, we measured the impact of vaccination on General Practitioner [GP] reported new episodes of illness for clinically diagnosed influenza-like illness [ILI] and total acute respiratory infection [TARI] during eight consecutive winters, adjusting for potential confounders using multivariable techniques. Although the study failed to demonstrate the effectiveness of influenza vaccine, we identified important potential confounding related to a greater likelihood of vaccinees than non-vaccinees to consult with a GP for respiratory infections. Future researchers should consider and account for this phenomenon
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Infecções Respiratórias
/
Estações do Ano
/
Doenças Cardiovasculares
/
Estudos de Casos e Controles
/
Fatores de Risco
/
Inibidores de Hidroximetilglutaril-CoA Redutases
/
Influenza Humana
/
Clínicos Gerais
/
Pandemias
/
Hipertensão
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
J. Infection Public Health
Ano de publicação:
2010
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