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Evaluation of inter-pandemic influenza vaccine effectiveness during eight consecutive winter seasons in England and Wales in patients with cardiovascular risk factors
Journal of Infection and Public Health. 2010; 3 (4): 159-165
em Inglês | IMEMR | ID: emr-125903
ABSTRACT
We evaluated the effectiveness of inactivated influenza vaccine in persons aged >/= 45 years with co-morbidities [including essential hypertension] likely to have prompted consideration of prophylactic statin therapy. Using case-control analyses, we measured the impact of vaccination on General Practitioner [GP] reported new episodes of illness for clinically diagnosed influenza-like illness [ILI] and total acute respiratory infection [TARI] during eight consecutive winters, adjusting for potential confounders using multivariable techniques. Although the study failed to demonstrate the effectiveness of influenza vaccine, we identified important potential confounding related to a greater likelihood of vaccinees than non-vaccinees to consult with a GP for respiratory infections. Future researchers should consider and account for this phenomenon
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Infecções Respiratórias / Estações do Ano / Doenças Cardiovasculares / Estudos de Casos e Controles / Fatores de Risco / Inibidores de Hidroximetilglutaril-CoA Redutases / Influenza Humana / Clínicos Gerais / Pandemias / Hipertensão Limite: Feminino / Humanos / Masculino Idioma: Inglês Revista: J. Infection Public Health Ano de publicação: 2010

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Infecções Respiratórias / Estações do Ano / Doenças Cardiovasculares / Estudos de Casos e Controles / Fatores de Risco / Inibidores de Hidroximetilglutaril-CoA Redutases / Influenza Humana / Clínicos Gerais / Pandemias / Hipertensão Limite: Feminino / Humanos / Masculino Idioma: Inglês Revista: J. Infection Public Health Ano de publicação: 2010