[ study on prevalence of helicobacter pylori in acute coronary syndrome]

ABSTRACT

Coronary artery disease is the main cause of mortality in developing countries like Iran. Due to failure of classic risk factors to completely explain epidemiologic variability of the disease, other risk factors, for example infection diseases are under investigation. One of these infectious agents is Helicobacter pylor which have been investigated in numerous studies. This study was designed to assess the controversies about Helicobacter pylor prevalence in acute coronary syndrome. All the patients with ACS including unstable angina and myocardial infarction who referred to Fatemie Hospital between 20 Feb 2003 to 9 Feb 2004 and were admitted in CCU ward were included in this cross-sectional study. A total of 411 patients with ACS were evaluated for prevalence of Helicobacter pylor antibody. Mean age of patients was 59.97and 56% of them were male. The serological test for Helicobacter pylor infection was positive in 45.6%of cases, negative in 43.8% and borderline in 10.6% of patients. 191 patients had unstable angina and 220 patients had myocardial infarction. This study showed that prevalence of Helicobacter pylorinfection in patients with acute coronary syndrome was not high. Thus acute or chronic infection with Helicobacter pylor could not be a risk factor for ACS