[Effect of tanacetum parthenium in treatment of migraine headache comparing to placebo]

ABSTRACT

Migraine is secondary common cause of headache. Headache is the most common clinical syndrome of pain. There are several methods in treatment of migraine including herbal medicine. Tancetum parthenium, a kind of chrysanthemum from kacny race is traditionally used for treatment of headache. The aim of this research was to assess the effect powder of Tanacetum parthenium in treatment of migraine. This is a double blinded clinical trial that lengthened for 8 months from 2004 to 2005. Patients were selected from Imam Reza hospital neurology clinic, Mashhad University of medical science. We had two groups drug and placebo group. 45 people were introduced in each group. In our research, 4 patients in drug group and 11 patients in placebo group were missed. Patients with migraine that their headache frequency was more than 3 times in a month were included in our research. Severity and frequency of headache and kind of prescribed drug were variables that investigated in this study. After 15 days, 29 people [70.7%] in drug group and 21 people [61.8%] in placebo group were good or better than before treatment [p=0.49]. There was a significant improvement in severity and frequency of headache in drug group compared to placebo group only 105 days after treatment [P=0.01]. This research shows that Tanacetum parthenium is significantly more effective than placebo [p<0.05]. So use of this drug is suggested in treatment of migraine