Annals of Saudi Medicine. 2012; 32 (3): 309-311
em Inglês
| IMEMR
| ID: emr-128513
ABSTRACT
Toxic epidermal necrolysis represents an immunologic reaction to a foreign antigen and is most often caused by drugs. Atorvastatin, a blood cholesterol-lowering agent, is a recognized cause of rhabdomyolysis; while naproxen, a widely used nonsteroidal anti-inflammatory drug, is a known cause of photo-induced skin lesions. We report the first fatal case of drug-induced toxic epidermal necrolysis associated with severe muscle necrosis due to the use of a nonsteroidal anti-inflammatory drug and a statin with very high levels of creatine phosphokinase leading to acute kidney injury, disseminated intravascular coagulation, and complete skin necrosis leading to death
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Pirróis
/
Rabdomiólise
/
Anti-Inflamatórios não Esteroides
/
Naproxeno
/
Creatina Quinase
/
Coagulação Intravascular Disseminada
/
Ácidos Heptanoicos
Tipo de estudo:
Relato de Casos
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Ann. Saudi Med.
Ano de publicação:
2012
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