Immunohistochemical analysis of P53 protein in odontogenic cysts
SDJ-Saudi Dental Journal [The]. 2010; 22 (4): 167-170
em Inglês
| IMEMR
| ID: emr-129282
ABSTRACT
The p53 is a well-known tumor suppressor gene, the mutations of which are closely related to the decreased differentiation of cells. Findings of studies on immunohistochemical P53 expression in odontogenic cysts are controversial. The present study was carried-out to investigate the immunohistochemical expression of P53 protein in odontogenic cysts. Thirty paraffin blocks of diagnosed odontogenic cysts were processed to determine the immunohistochemical expression of P53 protein. Nine of the 11 odontogenic keratocysts [81.8%] expressed P53, one of three dentigerous cyst cases expressed P53, while none of the 16 radicular cysts expressed P53 protein. The findings of the present work supported the reclassification of OKC as keratocystic odontogenic tumor
Buscar no Google
Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Imuno-Histoquímica
/
Cisto Dentígero
/
Cistos Odontogênicos
/
Cisto Radicular
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Saudi Dent. J.
Ano de publicação:
2010
Similares
MEDLINE
...
LILACS
LIS