Childhood hemolytic uremic syndrome in Jordan
Jordan Medical Journal. 2010; 44 (1): 36-41
em Inglês
| IMEMR
| ID: emr-129361
ABSTRACT
Hemolytic Uremic Syndrome [HUS] is the most common cause of Acute Kidney Injury [AKI] in the developed countries. It consists of Microoangiopathic Hemolytic Anemia [MAHA], AKI and thrombocytopenia. To review the outcome of childhood Diarrhea-associated Hemolytic Uremic Syndrome [D+HUS] presenting to the pediatric department at Jordan University Hospital [JUH]. In this retrospective study war reviewed the medical rectors of children presenting to JUH between January 1977 and January 2008 with D+HUS. There were 21 patients [15 girls and 6 boys]. Age ranged from 6 months to 11 years. 8 children [38%] had Entamoeba histolytica infection. 57% needed peritoneal dialysis. Central nervous system manifestations included drowsiness in 8 patients [38.1%], limb weakness in 2 patients [9.5%], seizures in 9 patients [43%], irritability 3 patients [14%], transient blindness in 2 patients [9.5%], and uremic encephalopathy in 1 patient [4.8%]. Complete recovery in 11 patients [52.4%], chronic kidney disease in 6 patients [28.6%], central nervous system deficit in 2 patients, and death in 2 patients [9.5%]. There was no correlation between the outcome and the presence of leukocytosis, thrombocytopenia, severity of renal failure, hyponatremia, or hypertension [p<0.05]. Our data highlights the importance of D+HUS in the pediatric age group. In addition, it emphasizes its manifestations, complications, and outcome:
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Pediatria
/
Estudos Retrospectivos
/
Resultado do Tratamento
/
Entamoeba histolytica
/
Injúria Renal Aguda
/
Síndrome Hemolítico-Urêmica
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Jordan Med. J.
Ano de publicação:
2010
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