[Histopatological evaluation of pulpal response of primary teeth following pulpotomy with formocresol, ferric sulfate and Iranian mineral trioxide aggregate]

ABSTRACT

Formocresol is one of the most common pulpotomy madicaments in the primary teeth. Because of its systemic and local side effects, it may be essential to use another material instead of formocresol. The purpose of this study was to assess the pulpal response after pulpotomy in the primary teeth using 3 different agents formocresol, ferric sulfate and Iranian MTA. In this randomized clinical trial, 30 teeth of 14 children that were to be extracted because of orthodontic treatment were selected. These teeth were divided randomly into three groups of 10. The teeth in each group were pulpotomized with formocresol, ferric sulfate and MTA, respectively. These teeth were extracted after 2 months and the pulpal responses were evaluated according to the degree of inflammation and extent of pulpal involvement. Dentinal bridge formation was also evaluated. Finally, the data were analyzed with Kruskal-wallis and sign test. In the formocresel group, moderate and severe inflammation was seen in 5 cases, necrosis in 4 cases, and abscess in 1 case. In the ferric sulfate group, moderate and severe inflammation was seen in 5 cases, necrosis in 1, abscess in 1, and internal rsorption in 1 case. In this group, dentinal bridge was formed in 1 case. In the MTA group, severe inflammation was seen in 1 case and dentinal bridge formation in 7 cases. Kruskal-wallis test revealed that inflammation in the MTA group was less than that of formocresol and sulfate ferric, significantly [p < 0.05]. Sign test showed that dentinal bridge formation in the MTA group was more than that in formocresol and ferric sulfate, significantly [p < 0.05]. Based on the results of this study, Iranian MTA can be used in primary teeth pulpotomy