Histological and histochemical changes in the testis of Albino rat following zinc deficient diet

ABSTRACT

The present study showed that severe zinc deficiency [one part per million = 1- PPM] led to disorganization of the germinal epithelium which was accompanied by severe reduction in the germinal layers to the extent that some tubules were lined only by two layers of cells. The contents of D.N.A. and R.N.A. decreased in the spermatogenic cells and in Leydig cells while fat was accumulated in these cells. The activity of succinic dehydrogenase was increased in proportion to the magnitude of zinc deficiency