Histological studies on pancreatic tissue in diabetic rats by using wild cherry

ABSTRACT

A lot of debate about wild cherry is published especially it's hypoglycemic and antioxidant effects, this study is conducted to see the histological, biochemical and morphometrical changes in rats pancreas. Wild cherry possesses a mild stimulatory action on pancreatic islets. Also it can be regarded as protective to islets of Langerhans in diabetic rats. Fifteen Rats were employed in this study. they were divided into 3 groups [5 normal controls, 5 given alloxan, 5 Treated with cherry herbs after given alloxan]. The normal control group resulted, no abnormalities in pancreatic tissue, while the group of alloxan rats showed marked reduction in the diameter of islets of langerhans with necrosis cells, it also showed increase in blood sugar [as compared with the control Group]. The wild cherries group showed apparently normal pancreatic tissue and islets of langerhans diameter, also normal blood sugar [as compared with the alloxan group]. Islets cells destruction was evident after alloxan administration, while protection action was prominent after wild cherry in diabetic rats