[Profile of biochemical markers in cystic fibrosis. prospective study about 13 cases]

ABSTRACT

To study the disturbances of biochemical parameters which make it possible to evaluate the nutritional state during the cystic fibrosis. Prospective study about 13 cases hospitalized over a 7 months period, whose age varies between 2 months and 12 years and adressed for a suspicion of cystic fibrosis. For all the patients we made a clinical collection of the data and a biochemical study. Hypoprotidemia [protidemia < 60 g/l] was noted in 6 cases. Three cases presented a hypocalcaemia [calcemia < 2.20 mmol/l]. A hypomagnesaemia [magnesemia < 0.70 mmol/L] was observed in 2 cases. The totality of the patients presented zinc concentrations lower than the normal value. Iron concentrations lower than the normal [11- 24 mmol/l] was noted in 5 cases. Four patients [4/13] presented a concentration of iron between 11.2 and 20 mmol/l, whereas a high concentration [32.3 mmol/l] was noted in only one case [7.7%]. The study of the biochemical parameters allowed to evaluate the variation of some trace elements in cystic fibrosis and their consequence on the nutritional state of the patients, which constitutes an essential element for the assessment of these patients