Teratogenic effects of thiabendazole on chicken embryos

ABSTRACT

The teratogenic effects of Thiabendazole fungicide were studying in chicken embryos, using five different concentrations, including the recommended field rate. Embryonated eggs were treated by immersion in aqueous dilutions of fungicide on the 6th day of incubation. Survival embryos were subjected to morphological, visceral, and skeletal examinations. Delayed ossification and extra-rib were observed as skeletal anomalies. Alkaline phosphatase activities of several tissues, i.e. the thigh bones, cervical and thigh muscles showed an inhibition correlated with fungicide concentrations