comparative study of clinical and histopathological response of different modalities of therapy used in the management of IUCD induced menorrhagia

ABSTRACT

Removal of IUCD as a result of menorrhagic side effects was reported to occur in 8% of IUCD users. In this study, 75 women with Cu. T. 200 for more than 3 months with irregular menstrual bleeding were treated ether by metronidazole [Flagyl], mefenamic acid [Ponstan] ehamsylate [Dicynone] or a combination of these 3 drugs for 3 consecutive cycles. Endometrial biopsy was carried out before and after therapy to identify any possible changes in the histopathological pattern. The use of combined treatment of all the 3 drugs gave the most significant result in reducing the amount but not the duration of the flow in 47.4% of patients