Scedosporium apiospermum brain abscess: an emerging challenge

ABSTRACT

Invasive fungal infection of the brain in immunocompromised patients is frequently fatal. New opportunistic fungal infections with resistance to many antifungal agents are identified. Scedosporium species [Pseudallescheria boydii] is one of them. Fortunately, the infection is not common and only occasional cases are encountered. A case of Scedosporium brain abscess was treated in a relatively preserved, immunocompromised elderly lady who did not respond to antifungal treatment with voriconazole. This is the first case of Scedosporium brain abscess to be reported in the Gulf. An emerging medical challenge is highlighted and the literature reviewed