Analgesic and antipyretic activities of leaf of moringa oleifera Lam

ABSTRACT

Moringa oleifera Lam., is a common plant found throughout India and its different parts are used for various medicinal purposes by local people. It has also been mentioned briefly in literature of traditional medicine but it has not been investigated scientifically for its pharmacological effects. In the present study, it was investigated for analgesic effect against thermal stimuli using Eddy's hot plate test and Analgesiometer test and for antipyretic effect in DPT induced pyrexia in experimental animals. It was found that M. oleifera leaf produced analgesic effect, which started at 20 minutes and persisted up to 120 minutes. The peak effect was found at 60 minutes. Similarly, it also produced significant antipyretic effect, which started at 30 minutes of drug administration and continued till 150 minutes. It was concluded that M. oleifera leaf possess significant analgesic and antipyretic effect