Endotracheal intubation in children undergoing cleft lip surgery. A comparative study between propofol and halothane

ABSTRACT

Endotracheal intubation is one of important step during the administration of general anesthesia. It is more so in pediatric patients with associated deformities like cleft lip and palate. Propofol, with its profound depressant effect on the airway reflexes, has a quick and smoother induction. Similarly, halothane is least expensive volatile anesthetic, sweaty to inhale and because of its safety profile. The intubating conditions with the use of intravenous propofol is superior to inhalational halothane with oxygen for tracheal intubation without muscle relaxants in children who undergo cleft lip surgery. In this prospective randomized study, 50 ASA I patients who where aged three to nine months, who were scheduled for cleft lips surgeries were included. Both group received halothane 3% by face mask with monitors attached [pulse oximeter, ECG, NIBP]. I.V line inserted, first group[propofol group] once patients become sleepy and respiration became regular and stop movement they received 2mg/kg propofol and E.T.T attempt within 0ne min.2nd group inhalational[halothane Group] until pupil been central and constricted and E.T.T attempted within 5 min. The intubation conditions were assessed by using Steyn's modification of the Helbo - Hansen intubating conditions score. The intubating conditions were better in group A than in group B. The group A patients [88%] significantly had more clinically acceptable intubating conditions than in group B[52%], [p=0.0015]. The intubating conditions with the use of intravenous propofol 2mg/kg is superior to inhalational 3% halothane with oxygen for tracheal intubation without muscle relaxants in children who undergo cleft lip surgery