Distal 10 q trisomy: a clinically recognizable syndrome

ABSTRACT

The clinical abnormalities encountered in this female child with partial trisomy for the distal part of the long arm of chromosome 10 [10q24 -qter] are similar to previously reported cases with craniofacial dysmorphia, hand and feet anomalies, growth retardation, delayed development and hypotonia. Trisomy for this segment was due to paternal balanced translocation. The importance of chromosome analysis on all cases with multiple congenital abnormalities/mental retardation is stressed