Alopecia following oral acyclovir for the treatment of Herpes simplex keratitis

ABSTRACT

The authors report acyclovir-induced alopecia in a patient treated for herpetic keratouveitis. A 32-years-old female was diagnosed with herpetic keratouveitis. She was placed on prednisolone acetate [l%] suspension four times a day, atropine sulfate [1%] thrice a day and oral acyclovir 400 mg twice-daily Three weeks following oral acylovir, keratouveitis improved, but she developed alopecia without any drug eruptions. Oral acyclovir was discontinued. Three months later, alopecia completely resolved. Alopecia may be considered a possible complication following oral acyclovir