Assessment of G6PD role in anaemia of chronic renal failure

ABSTRACT

Thirty cases of chronic renal failure were studied, 20 of them were on regular hemodialysis and the remaining ten were treated conservatively. These cases were subjected to full clinical examination, complete hemogram together with reticulocytic count and biochemical measurements as B.U.N., creatinine, calcium and phosphorus. Ten normal cases [control] were subjected to the same procedures. The results showed that non of these thirty cases exhibited decreased G6PD activity. On the contrary, there was a significant increase in G6PD activity in both groups of patients which is most likely contributed to the younger age erthrocyte population. Thus, it seems that G6PD has no role in anemia of chronic renal failure and its routine measurement has no place in the control and treatment of these patients