Association of BMI with elevated values of CK-MB and cTnT in acute myocardial infarction

ABSTRACT

To determine the association of BMI with serum levels of cTnT and CK-MB isoenzyme in patients presented to hospital emergency with suspected myocardial infarction and in healthy individuals. Comparative cross sectional study. This study was conducted at Post graduate medical institute, Lahore in collaboration with Punjab Institute of Cardiology Lahore from July 2010 to Dec 2010. Serum concentration of CK-MB and Cardiac Troponin T were estimated in 80 patients of AMI [40-60 years of age both sexes] by Immunological UV assay and electrochemiluminescence immunoassay [ECLIA] respectively. 40 healthy controls were matched for age and sex. Low BMI was observed in patients with both sexes. The values of both CK-MB and cTnT were markedly raised in patients with acute myocardial infarction. In the present study higher prevalence of risk factors and MI were seen in patients even with BMI < 23 kg/m 2.Therefore recognition and adoption of BMI cutoffs represent a major step forward in redefining the risk stratification among Pakistanis