need for new anti-hepatitis C virus therapeutic strategies targeting the cellular micro-ribonucleic acids?

ABSTRACT

Infection with the hepatitis C virus [HCV] is a worldwide problem. Patients with chronic HCV infection who are non-responders to standard therapy represent a growing population within the HCV epidemic.Novel, more efficient and tolerable therapies are urgently needed. This review discusses the recent results showing that targeting miR-122, a micro-ribonucleic acid [MicroRNA] that enhances HCV replication, is a new anti-HCV therapy with a high barrier to resistance