Candida albicans infection of peptic ulcer

ABSTRACT

Endoscopic samples from 23 cases with gastric ulcers and 20 cases with duodenal ulcers were studied for the prevalence of Candida albicans using Gram stain and germ tube test. Cases were selected on the basis of paucity of ulcer symptoms and little response to medical to medical therapy. Fungal material was found in ulcer base in 51% of cases. Fungal gastric ulcers tended to be larger in diameter and more often suspected to be malignant, and occurs in older age group. There was no difference in treatment regimens between fungal ulcers and non- infected ulcers. With the present state of knowledge anti-fungal agents advised when ulcers are colonized by Candida in non elderly patients without underlying diseases