Diabetic foot infections

ABSTRACT

The objective of this study is to know the frequency of methicillin resistant Staphylococcus aureus and its antibiotic sensitivity in diabetic foot infections in our setup. Cross sectional descriptive study. Surgical Department, Khyber Teaching Hospital, Peshawar. January 2008 to January 2010. A total of 84 patients, including 64 males and 20 females. Patient's identity, age, gender and the bacterial isolate on culture and sensitivity report were noted on a standardized proforma and analyzed on SPSS version 16.0. Patients of 18 years and both gender with type I and II Diabetes mellitus, diabetic foot ulcers of Wagner Classification System Grade 1 to 5 of 3 weeks duration, with infection and with no evidence of healing were enrolled in the study. The overall mean age of patients was 60.8 years +/- 6.5SD with 9.2 +/- 0.5% HbA1c level. Frequency of methicillin resistant Staphylococcus aureus was 28.57%. Methicillin sensitive Staphylococcal aureus [51.19%], Pseudomonas aeruginosa [48.80%] and Escherichia coli [46.42%] were the common organism cultured. Methicillin resistant Staphylococcus aureus showed 100% sensitivity to Vancomicin, Linezolid, Meropenem, Imepenem and Pipracillin/tazobaclam. There is an alarming trend of increase in methicillin resistant Staphylococcus aureus because of indiscriminate use of antibiotics in our set up which should be discouraged and a detailed knowledge of bacterial susceptibility to antimicrobial agents is necessary