Effects of oral administration of monensin on serum glucose, AST, and arginase of holstein cows during transition period
Iranian Journal of Veterinary Research. 2008; 63 (1): 1-5
em Persa
| IMEMR
| ID: emr-146233
ABSTRACT
In the present study, under typical management conditions of dairy farms in Iran, the effect of oral administration of on serum glucose, AST and arginase[indices of liver injuries] of oral monensin was assessed. Thirteen multiparous Holstein cows were blocked into a control and an experiment group from 3 weeks prepartum to 45 days postpartum according the number of their calvings. The groups received similar diets. The experiment group received monensin added to grain mix at 340 mg/head/day during prepartum weeks, 160-480 mg/head/day during first two weeks postpartum, and 350 mg/head/day during days 15-45 postpartum. Blood samples were obtained at days -20 and -10 prepartum, and days 4, 15, 25, 35 and 45 postpartum to determine serum glucose, AST, and arginase. Serum glucose decreased significantly [p = 0.025] in the control group from day 10 prepartum to day 15 postpartum. In the experiment group it increased significantly [p = 0.049] from the beginning of the experiment to day 35 postpartum. On day 15 postpartum, serum glucose showed a tendency [p = 0.07] for significant difference between groups. The level of ASTwas higher in the experiment group from day 10 prepartum to day 25 postpartum with a significant difference [p = 0.011] on day 10 prepartum. There was no significant difference in serum arginase activity between control and experiment groups [p > 0.05]. Administration of monensin mixed with diet can result in better functions of the liver, increase [or prevention of decrease] in serum glucose during peripartum weeks. It appears that changes in the dose of the drug during the early postpartum days [due to changes in dry matter intake] cannot affect the positive effect of monensin. The positive effect of monensin can be started prepartum; thus, its administration from prepartum transition period continued to postpartum weeks is recommended
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Arginase
/
Aspartato Aminotransferases
/
Glicemia
/
Bovinos
/
Período Pós-Parto
Limite:
Animais
Idioma:
Persa
Revista:
Iran. J. Vet. Res.
Ano de publicação:
2008
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