High incidence of dyslipidemia in obese type 2 diabetics

ABSTRACT

To ascertain the effect of Body Mass Index [BMI] on plasma lipid profile in type 2 diabetes mellitus [T2DM]. Comparative, observational study Army Medical College, Rawalpindi from Jan 2007- June 2010. Sample size was 60, subdivided in to two groups. Group 1 comprising on 30 type 2 diabetics with BMI /=28. Blood glucose, HbA[1c] plasma cholesterol and triglyceride levels were determined. Group 1 consisted of 56% males and 44% females, whereas Group 2 had 54% males and 46% females. Mean age to develop T2DM for group 1 was 44.60 +/- 1.22 years and for group 2 was 42.13 +/- 0.86 years. BMI of group 1 was 20.29 +/- 0.56 and Group 2 was 28.95 +/- 0.26. Mean plasma cholesterol and plasma triglyceride levels of group 2 diabetics were significantly higher [p< 0.001] as compared with group 1 non obese diabetics. Whereas, mean plasma glucose [p< 0.01] and Glycosylated hemoglobin [p< 0.05] of group 2 diabetics were significantly higher as compared with group 1 non obese diabetics Dyslipidemia was more marked in obese type 2 diabetics. Whereas diabetics with low BMI had plasma lipid profile within normal range