High-sensitivity C-reactive protein and tumor necrosis factor alpha in pseudoexfoliation syndrome
Oman Medical Journal. 2013; 28 (1): 16-19
em Inglês
| IMEMR
| ID: emr-146724
ABSTRACT
The purpose of the present study was to determine the alterations in high-sensitivity C-reactive protein and Tumor Necrosis factor alpha levels in the blood serum of pseudoexfoliation syndrome cases [a disease with similar risk factors as systemic endothelial dysfunction diseases] and to compare the results with healthy individuals. High-sensitivity C-reactive protein and Tumor Necrosis factor alpha levels were determined in 30 cases with pseudoexfoliation syndrome and in 30 control patients of the same age and sex, by enzyme-linked immunosorbent assay. The levels of high- sensitivity C-reactive protein and Tumor Necrosis factor alpha in the blood serum of patients with pseudoexfoliation syndrome [3.95 +/- 0.88 mg/1, 332 +/- 0.99 pg/ml, respectively] were significantly higher than in the control group [2.51 +/- 0.79mg/l 0.43 +/- 0.15 pg/ml, respectively] p=0.001, p=0.002. The results suggest that increased levels of high-sensitivity C-reactive protein and Tumor Necrosis factor alpha, as markers of inflammation and peripheral endothelial dysfunction in pseudoexfoliation syndrome, may be risk factors for systemic and ocular manifestations of pseudoexfoliation syndrome
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Proteína C-Reativa
/
Ensaio de Imunoadsorção Enzimática
/
Fator de Necrose Tumoral alfa
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Oman Med. J.
Ano de publicação:
2013
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