Primary renal lymphoma: a rare cause of renal enlargement

ABSTRACT

Primary renal lymphoma [PRL] is a rare entity seen predominantly adult males. Patients usually have non specific manifestations and diagnosis may be delayeduntil they present with appreciable renal mass with recognizable clinical manifestations. Diagnosis depends upon ultrasound, CT scan [with exclusion of primary Iymphoma at other site and Iymph node enlargement], histopathology and immunohistochemistry. We present a case of fifty years old female who presented with dull abdominal pain and fever. On ultrasound a huge renal mass replacing the whole of the kidney was found. Ultrasound and CT scan for lymphadenopathy, organomegaly or any fluid was unremarkable. Histopathology of nephrectomy specimen received, showed replacement of renal tissue by sheets of large sized malignant lymphoid cells with vesicular nuclei. Immunohistochemistry confirmed its non epithelial origin and B- cell Non Hodgkin's lymphoma.