Histological, histochemical and scanning electron microscopic studies on epidermoid carcinoma of the floor of the mouth in male albino rats

ABSTRACT

Thirty male albino rats were used in this study to investigate and explore the malignant changes occurring in the floor of the mouth. The histological and histochemical results showed that developing carcinoma was of poorly differentiated type in most cases, in addition SEM examination of the surface [20 weeks after scratching] showed definite surface changes in the experimental group [painted with DMBA]