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impact of cytomegalovirus infection on mechanically ventilated patients in the respiratory and geriatric intensive care units
Egyptian Journal of Chest Diseases and Tuberculosis [The]. 2014; 63 (1): 239-245
em Inglês | IMEMR | ID: emr-154319
ABSTRACT
Reactivation of cytomegalovirus [CMV] has been reported in critically ill patients [especially elderly] lying in the intensive care units. So identifying such patients to treat is important. To detect the frequency of CMV infection in mechanically ventilated patients, and its correlation with patients' risk factors, and outcomes. The present study was carried out on 51 mechanically ventilated patients admitted to the Respiratory [20] and Geriatric ICU [31] of the Ain Shams University hospitals over a 3 month period. Serum CMV load was measured by real-time PCR. The overall rate of active CMV infection by RT-PCR among the studied populations was [68.6%], [77.4%] in patients of geriatric ICU versus [55%] in respiratory ICU patients. Comparison between CMV positive and negative cases showed a significant difference in the duration of mechanical ventilation and mortality rate. A statistically higher CMV load was recorded in respiratory ICU patients admitted due to exacerbation of chronic respiratory disease or stroke and developing ventilator associated pneumonia [VAP] or septic shock. Also there was a significant direct correlation between CMV load and age of the patient, duration of mechanical ventilation and duration of ICU stay CMV infection is frequent in mechanically ventilated critically ill patients especially the elderly. It is associated with poor outcomes, leads to increased mortality and morbidity in terms of increased ICU stay, longer duration of mechanical ventilation, and higher rates of nosocomial infections
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Respiração Artificial / Reação em Cadeia da Polimerase / Resultado do Tratamento / Estado Terminal / Cuidados Críticos / Hospitais Universitários / Unidades de Terapia Intensiva Limite: Feminino / Humanos / Masculino Idioma: Inglês Revista: Egypt. J. Chest Dis. Tuberc. Ano de publicação: 2014

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Respiração Artificial / Reação em Cadeia da Polimerase / Resultado do Tratamento / Estado Terminal / Cuidados Críticos / Hospitais Universitários / Unidades de Terapia Intensiva Limite: Feminino / Humanos / Masculino Idioma: Inglês Revista: Egypt. J. Chest Dis. Tuberc. Ano de publicação: 2014