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Phytochemical investigation on Euphorbia macrostegia [Persian wood spurge]
IJPR-Iranian Journal of Pharmaceutical Research. 2015; 14 (1): 243-249
em Inglês | IMEMR | ID: emr-154885
ABSTRACT
Euphorbia macrostegia or Persian wood spurge is one of the seventeen endemic plants of this genus in Iran. Three triterpenoids, 24-methylenecycloartan-3 beta -ol [1], butyrospermol [2] and cycloartenol [3] and three diglycerides, 1,2-di-O- alpha -linolenoyl-sn-glycerol [4], 1-O-linoleoyl-3- O-palmitoyl-sn-glycerol [5] and 1-O- alpha -linolenoyl-2-O-palmitoyl-sn-glycerol [6] were isolated from the hexane soluble part of methanol-dichloromethane extracts of the aerial parts of Euphorbia macrostegia Boiss. The structures of all compounds were elucidated using different spectroscopy methods including, [1]H NMR, [13]C NMR, HSQC, HMBC, EI-MS and IR. The triterpenes and the unsaturated fatty acids moieties of the diglycerides isolated from the plant were reported previously to have analgesic, anticancer, bactericidal and antifungal activity. Here, we show that E. macrostegia is a new source for the above mentioned biologically active compounds
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Triterpenos / Extratos Vegetais / Diglicerídeos / Compostos Fitoquímicos Idioma: Inglês Revista: Iran. J. Pharm. Res. Ano de publicação: 2015

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Triterpenos / Extratos Vegetais / Diglicerídeos / Compostos Fitoquímicos Idioma: Inglês Revista: Iran. J. Pharm. Res. Ano de publicação: 2015