Lipoprotein [a] levels in relation to severity of coronary artery disease in north Indian patients
Heart Views. 2013; 14 (1): 12-16
em Inglês
| IMEMR
| ID: emr-155405
ABSTRACT
Lipoprotein [a] [Lp [a]] is an established risk marker of coronary artery disease which is independent from other risk factors. The aim was to address the association between Lp [a] and CAD risk in North Indians. To evaluate whether high levels of lipoprotein [a] [Lp [a]] is a predictor of risk and is related to the severity of CAD. This was a cross-sectional study done on 360 patients presenting with chest pain. Coronary angiography revealed CAD in 270 patients and 90 patients without CAD. Lipoprotein [a] level, lipid profile, fasting blood glucose, anthropometric and clinical parameters were analyzed. Lipoprotein [a] 21.0 mg/dL is associated with the presence of coronary lesions [P = 0.0001]. A highly significant difference in Lp [a] levels was observed between normal coronaries vs. single-vessel disease, double-and triple-vessel disease [P < 0.0001]. Body mass index [BMI] was significantly raised in CAD group compared to normal coronary. Multivariate analysis found that Lp [a] was considered an independent predictor for severity of CAD and Lp [a] levels 21.0 mg/dL are associated with severe patterns of coronary atherosclerosis
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Triglicerídeos
/
Índice de Gravidade de Doença
/
Doença da Artéria Coronariana
/
Índice de Massa Corporal
/
Estudos Transversais
/
Fatores de Risco
/
Angiografia Coronária
Tipo de estudo:
Estudo de prevalência
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Heart Views
Ano de publicação:
2013
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