[Comparison of hepatic enzymes level between operating room's staff and other wards' personnel]

ABSTRACT

Long exposure to inhalant anesthetic gases especially halothane, among the known hepatotoxic agents, is a serious health risk for the staff of operating room. Current study was performed to compare the level of hepatic enzymes between Operating's room staff and other therapeutic wards' personnel out of the operating room. A total of 100 personnel from educational hospitals were included and their demographic and occupational information were recorded. Hepatic function tests and bilirubin were analyzed. In cases with values more than normal, in order to rule out hepatitis B and C, Hbs-Ag, Hbs-Ab and HCV-Ab were tested. Demographic information and employment span were comparable in two groups. The average of ALT, AST were significantly higher among operating room's staff in comparison with the other group [P<0.05] and there was no significant difference between the average of GGT and ALP between two groups [P>0.05]. ALT, AST and GGT indicated significantly increase with the age of personnel [more than 40 years] and increase in employment period [more than 15 years]. The operating room's staff in educational hospitals of Ardabil may be exposed to hepatotoxic agents that caused significant rise in hepatic enzymes