Dysbiosis in Ukrainian children with irritable bowel syndrome affected by natural radiation

ABSTRACT

Microbiota has an important role in human metabolism, nutrition, immunity, and protection against colonization by pathogenic microorganisms. Radiation can harm the beneficial members of the gastrointestinal tract flora. Our study included 75 rural children population aged 4-18, who lived in contaminated area exposed to natural environmental radiation with clinically symptom of irritable bowel syndrome and 20 healthy urban participant aged 5-15 as control group. The intestinal bacterial microbiota was examined from stool samples. Our results indicated the population levels of microbiota such as Enterobacter, Enterococcus, Lactobacillus and Bifidbacterium in caecal contents in 61 subjects [81.3%] was significantly less than in control group. We investigated alternation of the intestinal microbiota affecting by ionizing radiation in children with clinically syndrome of irritable bowel syndrome