In situ characterization of B-and T-lymphocytes in basal cell carcinoma of the head and neck region
EMHJ-Eastern Mediterranean Health Journal. 1997; 3 (1): 58-67
em Inglês
| IMEMR
| ID: emr-156450
ABSTRACT
Twenty cases of basal cell carcinoma [BCC] of the head and neck region were examined immunohistochemically for the detection of T- and Blymphocytes. The results showed that the dense lymphocytic infiltrate surrounding neoplastic cells of BCC consisted chiefly of T-lymphocytes. The lymphocytic infiltrate revealed in parts a pattern of a small lymphocytic follicle with peripherally situated T cells and central B cells. The predominance of Tlymphocytes in BCC suggests a local cell-mediated immune response. However, the presence of B-lymphocytes indicates a possible humoral immune reaction. T cells may be responsible for regulating the proliferation, and thus the growth, of malignant epithelial cells in BCC
Buscar no Google
Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Imuno-Histoquímica
/
Linfócitos B
/
Carcinoma Basocelular
/
Linfócitos T
/
Anticorpos Monoclonais
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
East Mediterr Health J.
Ano de publicação:
1997
Similares
MEDLINE
...
LILACS
LIS