Triclabendazole in the treatment of established human fascioliasis
EMHJ-Eastern Mediterranean Health Journal. 1998; 4 (2): 244-251
em Inglês
| IMEMR
| ID: emr-156531
ABSTRACT
The tolerance and efficacy of triclabendazole CGP 23030, specially prepared for human use, were assessed in 50 patients in the chronic phase of fascioliasis. After clinical examination, investigation and ultrasonography of the liver and biliary system, triclabendazole 10 mg/kg, either as a single or split dose, was administered. The clinical picture was studied daily for six days and the investigations were repeated 6, 30 and 60 days after treatment. The drug was tolerated. Its side-effects, which included upper abdominal pain, mild fever and limited derangement of liver function, were considered negligible. The cure rate at 2 months was 94% when assessed by the disappearance of eggs in stools and 88% when assessed by both the absence of eggs in stools and of worms in the biliary system. The use of triclabendazole for the treatment of human fascioliasis was found to be justified
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Benzimidazóis
/
Fasciolíase
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
East Mediterr Health J.
Ano de publicação:
1998
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