Measles seroepidemiology among adolescents and young adults: response to revaccination
EMHJ-Eastern Mediterranean Health Journal. 2006; 12 (5): 573-581
em Inglês
| IMEMR
| ID: emr-156914
ABSTRACT
We evaluated the seroprevalence of measles antibody and response to measles re-immunization in 590 previously vaccinated adolescents and young adults; 263 were seronegative. To differentiate between primary and secondary vaccine failure, anti- measles IgM and IgG titres were assessed again 2- 4 weeks after revaccination in 144 [105 seronegative, 39 seropositive] individuals 75 seronegative participants responded to revaccination anamnestically [P < 0.001] and developed immunity 11 also showed IgM response [probably primary vaccine failure immunity]; 38 seropositive participants, remained seroprotected without significant increase in antibody titre [P = 0.577]. Primary vaccine failure was 4.7%; secondary vaccine failure was 27.1%. After revaccination, 87.3% were seroprotected
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Testes Sorológicos
/
Vacina contra Sarampo
/
Monitorização Imunológica
/
Sarampo
Limite:
Adolescente
/
Adulto
/
Humanos
Idioma:
Inglês
Revista:
East Mediterr Health J.
Ano de publicação:
2006
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