Salivary anti-Helicobacter pylori positivity among endoscopy patients with chronic liver disease

ABSTRACT

In this study, endoscopy patients with and without chronic liver disease [CLD] were examined and tested for Helicobacter pylori infection by detecting the presence of serum and salivary anti-H. pylori antibody. The validity of these measures was compared with Campylobacter-like organism analysis [gold standard] performed on patients requiring gastric biopsy. Among 114 patients with CLD and 50 without, the commonest endoscopy diagnosis was gastritis [27.2%]. Salivary H. pylori positivity was significantly associated with older age. Salivary anti-H. pylori antibody positivity showed low sensitivity [36.6%] and high specificity [75.8%] in CLD patients