Antiphospholipid syndrome and retinal vein occlusion in adults
EMHJ-Eastern Mediterranean Health Journal. 2004; 10 (4-5): 627-632
em Inglês
| IMEMR
| ID: emr-158330
ABSTRACT
Antiphospholipid antibodies may play and important role in the pathogenesis of retinal vascular occlusions; investigated the prevalence among 33 patients with retinal vein and artery occlusions and 80 controls. Prevalence was 33% and 5% respectively. Ophthalmic examination and fluorescein angiography showed that occlusions were due to ischaemic events. The 11 patients were diagnosed with antiphospholipid syndrome 9 patients were treated successfully with laser photocoagulation and anticoagulant and anti-aggregant therapy. Two patients with antiphospholipid antibodies associated with resistance to activated protein C had unfavourable outcomes. Our results suggest a correlation between antiphospholipid syndrome and retinal vein occlusions; we recommend a systematic search for antiphospholipid antibodies in occlusions of unexplained origin and laser photocoagulation treatment and long-term oral anticoagulant and anti-aggregant therapy
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Oclusão da Veia Retiniana
/
Angiofluoresceinografia
/
Estudos de Casos e Controles
/
Distribuição de Qui-Quadrado
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Administração Oral
/
Fotocoagulação a Laser
/
Anticorpos Antifosfolipídeos
/
Anticoagulantes
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
East Mediterr Health J.
Ano de publicação:
2004
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