Biological activity resulting from exposure to aquatic environmental genotoxic pollutants in northern Egypt
EMHJ-Eastern Mediterranean Health Journal. 2010; 16 (1): 82-88
em Inglês
| IMEMR
| ID: emr-158379
ABSTRACT
We estimated pollution in Lake Edku and the Mediterranean Sea, El-Maadiya Region, with 3 aromatic amines [1-naphthylamine, 2-naphthylamine and benzidine] in the muscle tissue of fish. There were marked seasonal variations in the aromatic amine levels. We also determined oxidative stress [blood glutathione, and catalase activity] and genotoxic effects [chromosomal aberrations and urinary metabolites] in fishermen from each area. The fishermen suffered from oxidative stress and had high levels of the urinary metabolite sulfanilamide [mean [microg/mg creatinine] Lake Edku 20.7, Mediterranean 14.5, controls 5.3]. Frequencies for total chromosomal aberrations were significantly raised in the peripheral blood lymphocytes of fishermen in both areas [frequency [per 100 metaphases] Mediterranean 67, Lake Edku 45, controls 14]
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Sulfanilamidas
/
Poluentes da Água
/
Dano ao DNA
/
Estresse Oxidativo
/
Peixes
/
Mutagênicos
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
East Mediterr Health J.
Ano de publicação:
2010
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