Hepatitis B surface antigen carrier rate in unvaccinated and vaccinated children with thalassaemia major at Bahawal Victoria Hospital, Bahawalpur, Pakistan
EMHJ-Eastern Mediterranean Health Journal. 2012; 18 (4): 378-381
em Inglês
| IMEMR
| ID: emr-158830
ABSTRACT
Screening of blood reduces but does not eliminate the risk of hepatitis B virus [HBV] infection in multi-transfused thalassaemia patients. This study was done to evaluate efficacy of HBV vaccination on hepatitis B virus surface antigen [HBsAg] carrier rate in children with thalassaemia major receiving multiple blood transfusions. In a cohort study conducted at a hospital in Bahawalpur, Pakistan, during 2009-10, children with thalassaemia major aged < 60 months who received more than 24 blood transfusions and were HBsAg negative at the time of first blood transfusion were included. Of 196 unvaccinated children, the seropositive rate was 12.2%; while among 218 children vaccinated during the first year of life via the Pakistan Expanded Programme on Immunization, the seropositive rate was only 0,9%. The HBV vaccine was highly effective in reducing the HBsAg carrier rate in children with thalassaemia aged < 5 years
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Portador Sadio
/
Estudos de Coortes
/
Vacinas contra Hepatite B
/
Talassemia beta
/
Antígenos de Superfície da Hepatite B
Tipo de estudo:
Estudo de incidência
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
East Mediterr Health J.
Ano de publicação:
2012
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