Synthesis and cardiotonic properties of 6- [3-Pyridyl] nicotinonitrile derivatives
Egyptian Journal of Pharmaceutical Sciences. 1990; 31 (1-4): 417-25
em Inglês
| IMEMR
| ID: emr-15995
ABSTRACT
A number of 6- [3- pyridyl] nicotinonitrile derivatives were synthesized for their potential cardiotonic activity. This was achieved by reacting ketones [1] with ethyl cyanoacetate to give [II] or [III] depending on the reaction conditions. Similarly cyclocondensation of the same substrates [I] with malononitrile afforded the corresponding derivatives [IV] or [V]
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Química Farmacêutica
Idioma:
Inglês
Revista:
Egypt. J. Pharm. Sci.
Ano de publicação:
1990
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