effect of small dose bupivacaine-fentanyl in spinal anesthesia on hemodynamic nausea and vomiting in cesarean section

ABSTRACT

To compare the hemodynamic, nausea and vomiting with small dose bupivacaine-fentanyl spinal anesthetic versus a conventional dose of spinal bupivacaine in parturients undergoing cesarean section. Forty patients aged 17-35 years old which underwent cesarean section were randomized into two groups. Group-A received spinal anesthesia with 8mg of bupivacaine and 10 micro g fentanyl, group B received 12mg bupivacaine. The mean dose of ephedrine needed was 4mg in group A and 11.75mg in group B [P=0.006]. The mean ratio of lowest systolic pressure to baseline systolic pressure was 0.75 for group A and 0.65 for group B [P=0.04]. Nausea and vomiting was observed in 10% of group A versus 20% in group B. Small dose of bupivacaine and Fentanyl provides good spinal anesthesia for cesarean section with less hypotension, nausea and vomiting