Effect of scaling and root planning on salivary 8- hydroxydeoxyguanosine levels: periodontitis

ABSTRACT

Periodontal disease is an inflammatory disorder in which tissue damage occurs through complex interactions between periodontal pathogens and components of the host defense mechanisms and oxidative stress is implicated in pathophysiology. Twelve subjects with periodontitis were selected and salivary samples were taken before treatment, after 3 weeks of treatment and after 10 weeks of the treatment for 8-OHdG levels [8-Hydroxydeoxyguanosine]. Salivary levels of 8-OHdG were significantly decreased with scaling and root planning. Thus, measurement of 8-OHdG may prove to be useful in identifying periodontal disease and risk of tooth loss