Role of Diosmin in the treatment of hemorrhoids

ABSTRACT

To determine the role of diosmin in the management of haemorrhoidal disease. Interventional study. Department of Surgery, Liaquat University Hospital Jamshoro/Hyderabad and Sindh Employees Social Security Institute [SESSI] Hospital Kotri, from 1[st] January 2003 to 31[st] December 2004. A total number of 147 patients [99 males and 48 females] with haemorrhoids presented to outpatient department. All of them after evaluation of symptoms and signs of haemorrhoidal disease were prescribed diosmin [Tab. Daflon 500-mg 2xBD] for four weeks and patients were reviewed weekly for four weeks. Improvement of symptoms and proctoscopic findings were observed, and comparison done between first visit and last visit. Patients were followed for the maximum period of six months. Out of total 147 patients 142 [96.5%] came up to 3-months and 136 [92.5%] followed up to 6-months. Out of these 136 patients 67 [49.3%] patients had no recurrence of symptoms while 43 [31.6%] patients had no improvements in symptoms and 26 [19.1%] patients had recurrence of symptoms after temporary relief. Therefore these 69 [50.7%] were submitted for surgery. It was concluded that diosmin improves haemorrhoidal symptoms significantly for sufficient time so patients should initially be treated with diosmin